Biology of Cancer

Scientific chairs: Professor Wiesław Wiktor Jędrzejczak ( Medical University of Warsaw ) Professor Ted Hupp ( Edinburgh Cancer Research Centre, University of Edinburgh )

Workshop venue
Hotel EXPLORIS, al. Wyzwolenia 57, 05-140 Serock, Poland

DRAFT PROGRAMME

25.06.2008 (Wednesday)
11.00 – 11.30	Meeting in Warsaw – PKiN – Palace of Culture and Science, Congress Hall – Departure to Serock Arrivals and registration
13.00 – 14.00	Lunch
14.00 – 15.00	Welcome address:	Prof. Maciej Żylicz (Foundation for Polish Science) Dr Philippe Arhets (Inserm) Prof. Urszula Hibner (CNRS)



15.00 – 19.30	Session 1 Leukaemia
Chair of session Professor Wiesław Wiktor Jędrzejczak (Medical University of Warsaw)
15.00 – 15.30	Professor Torsten Haferlach (MLL Münchner Leukämielabor GmbH) - Genetic characterization of human leukemia
15.30 – 16.00	Professor Klaus Michael Debatin (Comprehensive Cancer Center, Ulm University Hospital) -Apoptosis signaling pathways and tumor therapy .
16.00 - 16.15	Dr Alison Michie ( University of Glasgow ) - A novel mouse model of chronic lymphocytic leukaemia
16.15-16.30	Dr Ewa Marcinkowska ( University of Wroclaw , Faculty of Biotechnology) - Participation of VDR and C/EBP transcription factors in differentiation of human acute leukemia cells
16.30 – 16.45	Discussion
16.45 – 17.00	Coffee break
17.00 – 17.30	Professor Peter Krammer ( University of Heidelberg ) - ROS and T cell lymphoma treatment
17.30 – 18.00	Professor Wiesław Wiktor Jędrzejczak (Medical University of Warsaw ) - Accidental transplantation of human leukemia. Biologic implications
18.00 – 18.15	Dr Katarzyna Piwocka (Nencki Institute of Experimental Biology, PAS) - Bcr-Abl-mediated resistance to spindle poisons; the role of compromised mitotic checkpoint and p53 acetylation
18.15-18.30	Dr Grzegorz Przybylski ( Institute of Human Genetics ) - Molecular characterization of chromosomal alterations by combining of FT-CGH and LM-PCR
18.30.-18.45	Dr Grzegorz W. Basak (Medical University of Warsaw ) - ROR1, a newly described chronic lymphocytic leukemia-specific oncofetal antigen and receptor for Wnt5a is also expressed by subsets of other human tumors
18.45 – 19.00	Discussion
19.00-19.20	Dr. Tobias Grimm and Dr. Torsten Fischer (Deutsche Forschungsgemeinschaft) - "The DFG's Activities for the Promotion of Polish-German Scientific Cooperation - an Overview with a Focus on Funding Cancer Research
20.00	Barbecue Party

26.06.2008 (Thursday)
9.00 – 12.45	Session 2 Lung Cancer
Chair of session Professor Jacek Jassem (Medical University of Gdańsk)
9.00 – 9.45	Professor Jacek Jassem / Rafał Dziadziuszko ( Medical University of Gdańsk) - Proteomics in lung cancer translational research
9.45 – 10.15	Professor Lynne Bemis ( University of Colorado Health Sciences and Cancer Center , Aurora, CO USA ) - MicroRNA's and cancer
10.15 – 10.30	Dr Marcin Skrzypski ( Medical University of Gdańsk ) - Quantitative (q) RT-PCR 3-gene expression signature predicts survival in early-stage non-small cell lung cancer (NSCLC) patients (p)
10.30-10.50	Dr Dimitri Xirodimis ( Dundee , UK ) - Proteomics approaches to the UBL pathway in cancer
10.50 – 11.10	Mr. Vikram Narayan ( University of Edinburgh ) - Novel Protein Interactomics approach for discovering protein-protein interactions in the Interferon transcription system
11.10 – 11.30	Discussion
11.30 – 11.45	Coffee break
11.45 – 12.00	Ms Leila Akkari (IGMM CNRS) - Three-dimensional organisation and in vitro differentiation of early hepatic precursors.
12.00 – 12.15	Dr Wojciech Niedźwiedź (Oxford University/WIMM) - The role of FANCM of the Fanconi anemia tumour supressor pathway in DNA crosslink repair and genome integrity
12:15 - 12:45	Discussion
12.45 – 13.00	Joanna Sterzyńska-Lindberg (Foundation for Polish Science) - "The Focus programme - Activities for the Promotion of Polish-abrod Scientific Cooperation - an Overview with a Focus on Funding Cancer Research"
13.00 – 14.00	Posters Session and discussion
14.00 – 15.00	Lunch
15.00 – 19.30	Session 3 Brain tumor
Chair of session Professor Bożena Kamińska (Nencki Institute of Experimental Biology PAS
15.00 – 15.30	Professor Hiroko Ohgaki ( Pathology Group, International Agency for Research on Cancer, World Health Organization) –Pathology and Genetics of Brain tumors
15.30 – 16.00	Professor Bożena Kamińska (Nencki Institute of Experimental Biology PAS ) – Brain tumor-microenvironment interactions as novel target for therapy.
16.00 – 16.15	Ms Beata Lipska (Medical University of Gdansk, Dept. of Biology and Genetics and Institiute of Pediatrics ) – Neuroblastoma: biological insights into a clinical enigma. Are we on the right TR(a)Ks?
16.15 – 16.30	Dr Mike-Andrew Westhoff (University Children’s Hospital Ulm ) – Alternating forms of CAM-DR in Glioblastoma multiform
16.30 – 16.45	Msc Monika Szeliga ( Medical Research Center , PAS ) – Transfection with liver-type glutaminase (LGA) cDNA alteres gene expression and reduces viability, migration and proliferation of T98G glioma cells
16.45 – 17.15	Discussion
17.15 – 17.45	Coffee break
17.45 – 18.15	Professor Michael Weller (University Hospital Zurich, Department of Neurology) Prognostic biomarker of brain cancer
18.15 – 18.30	Msc Agnieszka Sawicka ( Institute of Atomic Energy Radioisotope Centre POLATOM ) - Engineered Antibodies Fragments scFvTU20 Radionuclide-labeled as Targeting Agents for Tumor Imaging and Therapy
18.30 – 18.45	Mr Sébastien Morisseau (INSERM) - Allogeneic MHC Class I conjugated to antitumor antibody can induces regression of syngenic tumor graft in vivo
18.45 – 19.00	Mr Julien Schmidt (INSERM) - Synthesis of new tetracyclic RGD peptides for specific tumor cell targeting
19.00 – 19.30	Discussion
20.00	Supper

27.06.2008 (Friday)
9.00 – 14.00	Session 4 Biology of thyroid and skin neoplasia
Chair of session Professor Barbara Jarząb (Comprehensive Cancer Centre Maria Skłodowska-Curie Memorial Institute Branch Gliwice)
9.00 – 9.30	Professor Jan W. A. Smit (Department of Endocrinology, Leiden University Medical Center, The Netherlands) - Targeted therapy of differentiated thyroid carcinoma, current practice and future perspectives
9.30 – 10.00	Professor Massimo Santoro (Dipartimento di Biologia e Patologia Cellulare e Molecolare ‘L. Califano, Universit_ di Napoli Federico II) – Biology of thyroid carcinoma (biological role and potential therapeutic targeting of the chemokine receptor CXCR4 in undifferentiated thyroid cancer)
10.00 – 10.15	Dr Anna Zebzda (Department of Transplantation Jagiellonian University Medical College) - The influence of HSP 90 inhibitors and Resveratrol on Multiple Myeloma cells biology
10.15 – 10.30	Dr Łukasz Kuźbicki ( Nicolaus Copernicus University , Department of Medical Biology, Institute of General and Molecular Biology) - COX-2 expression as a marker for diagnostics of pigmented skin lesions and for assessment of metastatic potential of human cutaneous melanoma
10.30 – 10.45	Discussion
10.45 – 11.15	Coffee break
11.15 – 11.45	Professor Barbara Jarząb (Comprehensive Cancer Centre Maria Skłodowska-Curie Memorial Institute Branch Gliwice) Genomics of thyroid carcinoma
11.45 – 12.00	Dr Halina Waś ( Jagiellonian University , Department of the Medical Biotechnology Krakow) - Role of heme oxygenase-1 (HO-1) in induction and progression of skin cancer
12.00 – 12.30	Discussion
13.00 – 14.00	Lunch
14.00 – 18.30	Session 5 Molecular and cell biology of cancer and cancerogenesis
Chair of session Professor Urszula Hibner (CNRS)
14.00 – 14.45	Professor Pierre Formstecher (Jean-Pierre Aubert Research Centre, Cancer Department) Stem cells in cancerogenesis
14.45 – 15.45	Professor Ted Hupp (Edinburgh Cancer Research Centre, University of Edinburgh) Tumour suppressor proteins
15.45 – 16.00	Dr Jerzy G. Maj (Department of Radiation Oncology, Memorial Sloan-Kettering Cancer Center) - Intestinal crypt regeneration: a lesson from ionizing radiation injury
16.00 – 16.30	Discussion
16.30 – 16.45	Coffee break
16.45 – 17.15	Professor Urszula Hibner (CNRS) Cancer cell adhesion, motility, and invasion
17.15 – 17.30	Msc Monika Mach ( University of Wroclaw ) - Gelsolin expression and cancer cell motility
17.30 – 17.45	Dr Ben Wielockx (Pathology - TUD) - The role of HIF prolyl hydroxylases during tumor development
17.45 – 18.00	Dr Gabriela Kramer-Marek ( Radiation Oncology Branch NIH, NCI) - Molecular Targeting of HER2 for Diagnosis and Therapy of Breast Cancer
18.00 – 18.30	Discussion
18.30 – 18.45	Closing statements (Foundation for Polish Science)
20.00	Supper

28.06.2008 (Saturday)
9.00	Departure to Warsaw by bus; then guided tour of Warsaw (optional)

Workshop programme in PDF format

Programme

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